Square-wave Voltammetric Determination of Ant-hypertension (Azilsartn medoxomil) and Real Samples of Biological Applications

Document Type : Original Article

Authors

Faculty of Science, Department of Chemistry, University of Kufa, Iraq.

Abstract

Voltammetry was used to study the electrochemical behavior of Remdesivir at a Glassy carbon electrode for the first time. The electrochemical behavior of (AZL) was novelty diagnosed in way through employment (CV, SWV) techniques. (AZL) showed an irreversible oxidation peak a about +1.490 Vat Glassy carbon electrode, the scan rate study in the range 0.02–5 V/s indicates that the process is an electrode process that is completely irreversible and oxidation of AZL on the surface of GCE is diffusion controlled. Optimum operational parameters and the effects of experimental conditions to achieve the best experimental conditions for the voltammetric determination of AZL at GCE have been investigated. An excellent linear dependence of the SWV oxidative peak current on the concentration of AZL was observed in the range of 10-100 ppm with limits of detection (LOD) and quantification (LOQ) of 0.059 and 0.19 ppm, respectively. In addition, excellent recovery results were obtained for the analysis of AZL in pharmaceutical injection and real samples. The proposed approach was effectively employed in the determination of AZL in pharmaceutical and real samples. The novel proposed procedure is quick and affordable; sample preparation is not required.

Keywords

Egyptian Academic Journal of Biological Sciences, D. Histology & Histochemistry
Volume 15, Issue 2
December 2023
Pages 59-71

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