Effect of Lead Toxicity on The Kidney of Nile Tilapia: Amelioration by Beta-MOS®

Document Type : Original Article

Authors

1 Department of Zoology, Faculty of Sciences, Suez Canal University, Ismailia, Egypt.

2 Department of Zoology, Faculty of Sciences, Suez Canal University, Ismailia, Egypt

3 Department of Pathology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt.

4 Department of Physiology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt

Abstract

The present study investigated the possible ameliorative effect of Beta-MOS®on lead-induced toxicity in Nile tilapia. A total of ninety O. niloticus (34.43 ± 0.31 g and 7 weeks age) were used in this study. Fish of mixed sex were divided into 4 groups. The first group which served as control received a basal diet (0% Beta-MOS®). The second group received a diet supplemented with 0.3% Beta-MOS®. The third group was exposed to 10 mg Pb acetate L-1 in water and received a basal diet. The fourth group was exposed to the same dose of Pb acetate (10 mg L-1) in water and given 0.3% Beta-MOS®. Initial and final weight as well as weight gain were recorded. Red blood cell count and hemoglobin concentration were determined. Creatinine plasma level was estimated as well as histopathological changes in the kidney. The lead acetate induced a significant reduction in final body weight, weight gain, red blood cell count and hemoglobin concentration than control. Moreover, creatinine was significantly increased in the lead group than control, with retrogressive changes in histopathological sections. Dietary Beta-MOS® ameliorated all the lead-induced perturbations in the tested parameters.  Dietary Beta-MOS® ameliorated lead acetate toxicity in Nile tilapia.

Keywords

Egyptian Academic Journal of Biological Sciences, D. Histology & Histochemistry
Volume 14, Issue 2
December 2022
Pages 31-45

Files

Share

How to cite

Statistics