Role of some functional materials in prevention of rats liver damage induced Aflatoxicosis

Document Type : Original Article

Authors

1 Biology Department/ College of Science, Tikrit University

2 Food Science Department-College of Agriculture-Tikrit University

3 Biology Department- Iraqia University

Abstract

This study was aims to investigate the ability of Aspergillus parasiticus NRRL 2999 on aflatoxins (AF) production on rice, as well as to detect the ability of 50, 100 and 150 mg of each functional materials (FMs) as ginseng extract (GS), whey protein (WP) and butylated hydroxyl toluene (BHT) on degradation of AF in liquid media, and its detoxification effects against 1 mg of AF on body weight and liver histopathological characterizes in growing rats after feeding for 21 days. The results showed the ability of Aspergillus parasiticus in production the AF after cultivation on rice at 28 º c for 10 days, as well as the effects of 100 and 150 mg FMs from GS, WP and BHT in degradation of AF produced in malt extract broth media. The interactions between FMs and AF were confirmed by the histological study on liver of treated rats revealed congestion, kupffer cells hyperplasia, dilated sinusoids and mononuclear cells infiltration in all liver.

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